<i>O</i>-Cyanobenzaldehydes Irreversibly Modify Both Buried and Exposed Lysine Residues in Live Cells

H Huan Ling (State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China) L Lin Li L Liping Duan (State Key Laboratory of Bioactive Molecules and Draggability Assessment, School of Pharmacy) W Weixue Huang (State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China) J Jiangnan Zheng (Department of Chemistry) S Shijie Zhang (State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China) X Xinling Li (Department of Chemistry, School of Science) X Xiaorong Qiu (State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China) Y Yang Zhou N Nan Ma (State Key Laboratory of Bioactive Molecules and Draggability Assessment, School of Pharmacy) X Xiaomei Ren (State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China) J Jinwei Zhang (State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China) Z Zhen Wang Y Yujun Zhao (State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China) R Ruijun Tian (Taizhou Research Institute) Z Zhi-Min Zhang (State Key Laboratory of Bioactive Molecules and Drugability Assessment, School of Pharmacy) K Ke Ding

Article Details

Volume / Issue Vol. 147, Issue 14
Published April 09, 2025
Pages 11955-11963
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (17)

H

Huan Ling

State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China

L

Lin Li

L

Liping Duan

State Key Laboratory of Bioactive Molecules and Draggability Assessment, School of Pharmacy

W

Weixue Huang

State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China

J

Jiangnan Zheng

Department of Chemistry

S

Shijie Zhang

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China

X

Xinling Li

Department of Chemistry, School of Science

X

Xiaorong Qiu

State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China

Y

Yang Zhou

N

Nan Ma

State Key Laboratory of Bioactive Molecules and Draggability Assessment, School of Pharmacy

X

Xiaomei Ren

State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China

J

Jinwei Zhang

State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, #345 Lingling Road, Shanghai 200032, China

Z

Zhen Wang

Y

Yujun Zhao

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China

R

Ruijun Tian

Taizhou Research Institute

Z

Zhi-Min Zhang

State Key Laboratory of Bioactive Molecules and Drugability Assessment, School of Pharmacy

K

Ke Ding