Intradermal delivery of lipophilic siRNAs enables prolonged skin retention and sustained gene silencing in a porcine model

H Hassan H. Fakih M Mohammad Zain UI Abideen M Mohamad Omar Rachid K Katherine Y. Gross T Thomas J. R. Ormsby V Vella M. Ross R Rosemary Gagnon C Christopher Dahlke R Raymond C. Furgal C Clemens Lochmann A Ashley Summers H Hanadi F. Sleiman (Department of Chemistry, McGill University, 801 Sherbrooke Street. W, Montreal, Quebec H3A0B8, Canada) S Sylvia M. Fürst S Shanté N. Jackson J Juliana O. Gordilho C Claire Bouix-Peter T Thibaud Portal Q Qi Tang (State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, Fudan University, Shanghai, China.) J John E. Harris A Anastasia Khvorova C Carine Blanchard J Julia F. Alterman

Article Details

Volume / Issue Vol. 17, Issue 1
Published February 03, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (22)

H

Hassan H. Fakih

M

Mohammad Zain UI Abideen

M

Mohamad Omar Rachid

K

Katherine Y. Gross

T

Thomas J. R. Ormsby

V

Vella M. Ross

R

Rosemary Gagnon

C

Christopher Dahlke

R

Raymond C. Furgal

C

Clemens Lochmann

A

Ashley Summers

H

Hanadi F. Sleiman

Department of Chemistry, McGill University, 801 Sherbrooke Street. W, Montreal, Quebec H3A0B8, Canada

S

Sylvia M. Fürst

S

Shanté N. Jackson

J

Juliana O. Gordilho

C

Claire Bouix-Peter

T

Thibaud Portal

Q

Qi Tang

State Key Laboratory of Genetics and Development of Complex Phenotypes, School of Life Sciences, Fudan University, Shanghai, China.

J

John E. Harris

A

Anastasia Khvorova

C

Carine Blanchard

J

Julia F. Alterman