Interface Architecture of a VHL-PROTAC Complex with and without Cullin-2

E Evan N. Whitford (School of Chemistry & Biochemistry) J Joshua D. Gilbert (Native MS Guided Structural Biology Center) M Marius M. Kostelic (Native MS Guided Structural Biology Center) A Aaron C. Ehlinger (Target Enabling Technologies, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States) T Tiffany A. Thibaudeau (Target Enabling Technologies, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States) S Shaun M. McLoughlin (Technology and Therapeutic Platforms, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States) V Vicki H. Wysocki

Article Details

Volume / Issue Vol. 148, Issue 19
Published May 20, 2026
Pages 19730-19737
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (7)

E

Evan N. Whitford

School of Chemistry & Biochemistry

J

Joshua D. Gilbert

Native MS Guided Structural Biology Center

M

Marius M. Kostelic

Native MS Guided Structural Biology Center

A

Aaron C. Ehlinger

Target Enabling Technologies, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States

T

Tiffany A. Thibaudeau

Target Enabling Technologies, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States

S

Shaun M. McLoughlin

Technology and Therapeutic Platforms, AbbVie, 1 N. Waukegan Rd, North Chicago, Illinois 60064, United States

V

Vicki H. Wysocki