Integrated single-cell and machine learning analysis identifies PMAIP1 as a novel biomarker for predicting prognosis and immunotherapy response in colorectal cancer

Xiangfang Li; Zihan Cai; Shoupeng Ding; Jinghua Gao; Yuanlin Wang; Yuqian Wu; Huangyan Zhang; Jiachuan Chen; Zongqiang Hu

doi:10.1038/s41598-025-32933-8

Integrated single-cell and machine learning analysis identifies PMAIP1 as a novel biomarker for predicting prognosis and immunotherapy response in colorectal cancer

X Xiangfang Li Z Zihan Cai (Key Laboratory of Biomedical Polymers-Ministry of Education, College of Chemistry and Molecular Sciences) S Shoupeng Ding J Jinghua Gao Y Yuanlin Wang (Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, State Key Laboratory of Synergistic Chem-Bio Synthesis, Zhengzhou Industrial Technology Research Institute of Shanghai Jiao Tong University, School of Chemistry and Chemical Engineering) Y Yuqian Wu H Huangyan Zhang J Jiachuan Chen Z Zongqiang Hu

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Article Details

Journal Scientific Reports

Volume / Issue Vol. 16, Issue 1

Published December 23, 2025

DOI 10.1038/s41598-025-32933-8

ISSN 2045-2322

Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (9)

X

Xiangfang Li

Z

Zihan Cai

Key Laboratory of Biomedical Polymers-Ministry of Education, College of Chemistry and Molecular Sciences

S

Shoupeng Ding

J

Jinghua Gao

Y

Yuanlin Wang

Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, State Key Laboratory of Synergistic Chem-Bio Synthesis, Zhengzhou Industrial Technology Research Institute of Shanghai Jiao Tong University, School of Chemistry and Chemical Engineering

Y

Yuqian Wu

H

Huangyan Zhang

J

Jiachuan Chen

Z

Zongqiang Hu

Integrated single-cell and machine learning analysis identifies PMAIP1 as a novel biomarker for predicting prognosis and immunotherapy response in colorectal cancer

Article Details

Journal Info

Authors (9)

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