Integrated metabolomics and network pharmacology reveals that icariin antagonizes malignant phenotypes in triple-negative breast cancer via AKT1/SRC/NFKB1-mediated PI3K‒AKT pathway inhibition
H
HaiYang Hu
S
Shenghan Gao
J
Jie Liu
W
Wen Wang
K
Kexin Chang
Y
Yulong Yin
(National Engineering Research Center of Industrial Enzymes)
X
Xianghua Liu
Q
Qingjie Meng
W
Wenzhen Shi
Y
Yonggang Lv
Article Details
Journal
Scientific Reports
Volume / Issue
Vol. 1, Issue 1
Published
July 25, 2026
ISSN
2045-2322
Publisher
Nature Portfolio
Authors (10)
H
HaiYang Hu
S
Shenghan Gao
J
Jie Liu
W
Wen Wang
K
Kexin Chang
Y
Yulong Yin
National Engineering Research Center of Industrial Enzymes
X
Xianghua Liu
Q
Qingjie Meng
W
Wenzhen Shi
Y
Yonggang Lv
Related Articles from this Journal
AI models of unstable flow exhibit hallucination
Ramdhan Wibawa, Birendra Jha
Aug 2026
10.1038/s41598-026-64023-8
The MCAA-YOLO + XPBI integrated model provides a hybrid intelligent measurement method for predicting the body weight of Hu sheep
Hang Zhang, Yuang Cheng et al.
Aug 2026
10.1038/s41598-026-64075-w
Application of iron nano-biofertilizers as a sustainable approach to enhance growth and micronutrient uptake in soybean
Ava Mohrazi, Reza Ghasemi-Fasaei
Aug 2026
10.1038/s41598-026-66011-4
Adolescents’ status-dependent public and private conformity to prosocial and antisocial decisions in a public goods game
Niloofar Saeedi, Khatereh Borhani et al.
Aug 2026
10.1038/s41598-026-64831-y
An explainable hierarchical capsule network framework for supporting expert sensory evaluation of herbal medicines with natural language generation
Hyein Lee, Dae-Hyun Jung
Aug 2026
10.1038/s41598-026-64156-w