Inhibition of the QPCT–PDIA4 axis rescues ΔF508 and N1303K CFTR in cystic fibrosis

Le Sun; Larry Rodriguez; Sandra Pankow; Jolene Diedrich; Ke Qin; Jianan Zhang; Xu Wu; Peng Wu; John R. Yates

doi:10.1038/s41467-026-74078-w

Inhibition of the QPCT–PDIA4 axis rescues ΔF508 and N1303K CFTR in cystic fibrosis

L Le Sun L Larry Rodriguez S Sandra Pankow J Jolene Diedrich (Multi-Omics Core, The Scripps Research Institute) K Ke Qin J Jianan Zhang X Xu Wu (State Key Laboratory of Soil Pollution Control and Safety, Department of Chemistry) P Peng Wu J John R. Yates

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published June 09, 2026

DOI 10.1038/s41467-026-74078-w

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (9)

L

Le Sun

L

Larry Rodriguez

S

Sandra Pankow

J

Jolene Diedrich

Multi-Omics Core, The Scripps Research Institute

K

Ke Qin

J

Jianan Zhang

X

Xu Wu

State Key Laboratory of Soil Pollution Control and Safety, Department of Chemistry

P

Peng Wu

J

John R. Yates

Inhibition of the QPCT–PDIA4 axis rescues ΔF508 and N1303K CFTR in cystic fibrosis

Article Details

Journal Info

Authors (9)

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