Inhibition of the cancer stem cell immune checkpoint SOAT1 suppresses regulatory T cell functions through a trans-cellular 20(S)-Hydroxycholesterol-GPR132 pathway in mice

Y Yahui Ding W Wanqi Fang R Ruiqing Xiang H Haitao Liu (State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences) M Menglin Huang (College of Integrated Circuits and Micro-Nano Electronics) Y Yingran Shen Y Ying Chen G Guohao Wang Z Zhaocai Zhou (State Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University) Y Yun Ling L Ling V. Sun Y Yuetong Wang S Steven X. Hou