Journal of the American Chemical Society

Inhibiting Glycolysis and Disrupting the Mitochondrial HK2–VDAC1 Protein–Protein Interaction Using a Bifunctional Lonidamine-Conjugated Metal Probe for Combating Triple-Negative Breast Cancer

L Ling Wang L Lingtan Kong (Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi’an, Shaanxi 710072, China) D Ding-Qi Zhang (Dr. Neher’s Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine) L Liuqi Ye (State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences) S Sang-cuo Nao (State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences) D Daniel Shiu-Hin Chan (Department of Chemistry) X Xueying Li Y Yutong Peng (School of Pharmacy, Faculty of Medicine) L Lijun Yang (Ballard Power Systems Inc.) C Chun-Yuen Wong (Department of Chemistry) V Vincent Kam Wai Wong (Dr. Neher’s Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine) W Wanhe Wang (Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi’an, Shaanxi 710072, China) H Hui Chao C Chung-Hang Leung (The State Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences)
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Article Details

Volume / Issue Vol. 147, Issue 17
Published April 30, 2025
Pages 14824-14836
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society
ISSN: 0002-7863 Physical Sciences

Authors (14)

L

Ling Wang

L

Lingtan Kong

Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi’an, Shaanxi 710072, China

D

Ding-Qi Zhang

Dr. Neher’s Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine

L

Liuqi Ye

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences

S

Sang-cuo Nao

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences

D

Daniel Shiu-Hin Chan

Department of Chemistry

X

Xueying Li

Y

Yutong Peng

School of Pharmacy, Faculty of Medicine

L

Lijun Yang

Ballard Power Systems Inc.

C

Chun-Yuen Wong

Department of Chemistry

V

Vincent Kam Wai Wong

Dr. Neher’s Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine

W

Wanhe Wang

Institute of Medical Research, Northwestern Polytechnical University, 127 West Youyi Road, Xi’an, Shaanxi 710072, China

H

Hui Chao

C

Chung-Hang Leung

The State Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences

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