Inflammation and mutational burden differentially associated with nivolumab or ipilimumab combination efficacy in colorectal cancer

M Ming Lei (State Key Laboratory of Chemical Resource Engineering, Institute of Computational Chemistry, College of Science) M Michael J. Overman J Jin Yao (School of Management, Shenzhen Polytechnic University) T Thierry André S Sara Lonardi H Heinz-Josef Lenz M Massimo Aglietta F Fabio Gelsomino R Ray McDermott K Ka Yeung Mark Wong M Michael A. Morse (Division of Medical Oncology Department of Medicine Duke University Medical Center Durham North Carolina USA) E Eric Van Cutsem (University Hospitals Gasthuisberg, Leuven, Belgium) A Alain Hendlisz D Dana B. Cardin B Bart Neyns A Andrew Hill (Bulmore Consulting) A Anuradha Krishnamurthy F Franklin Chen S Samith Kochuparambil R Robert R. Jenq (Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, The University of Texas MD Anderson Cancer Center) S Sandzhar Abdullaev B Beilei He R Ruslan Novosiadly S Scott Kopetz (University of Texas M.D. Anderson Cancer Center, Houston)

Article Details

Volume / Issue Vol. 16, Issue 1
Published October 06, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (24)

M

Ming Lei

State Key Laboratory of Chemical Resource Engineering, Institute of Computational Chemistry, College of Science

M

Michael J. Overman

J

Jin Yao

School of Management, Shenzhen Polytechnic University

T

Thierry André

S

Sara Lonardi

H

Heinz-Josef Lenz

M

Massimo Aglietta

F

Fabio Gelsomino

R

Ray McDermott

K

Ka Yeung Mark Wong

M

Michael A. Morse

Division of Medical Oncology Department of Medicine Duke University Medical Center Durham North Carolina USA

E

Eric Van Cutsem

University Hospitals Gasthuisberg, Leuven, Belgium

A

Alain Hendlisz

D

Dana B. Cardin

B

Bart Neyns

A

Andrew Hill

Bulmore Consulting

A

Anuradha Krishnamurthy

F

Franklin Chen

S

Samith Kochuparambil

R

Robert R. Jenq

Department of Genomic Medicine and MDACC Epigenomics Therapy Initiative, The University of Texas MD Anderson Cancer Center

S

Sandzhar Abdullaev

B

Beilei He

R

Ruslan Novosiadly

S

Scott Kopetz

University of Texas M.D. Anderson Cancer Center, Houston