Inferring chromosome segregation error stage and crossover in trisomic disorders with application to Down syndrome

Zhenhua Li

State Key Laboratory of Forage Breeding-by-Design and Utilization, Key Laboratory of Photobiology, Institute of Botany, Chinese Academy of Sciences

Wenjian Yang

Gang Wu

Ti-Cheng Chang

Zhongshan Cheng

Meenakshi Devidas

Department of Global Pediatric Medicine, St. Jude Children’s Research Hospital, Memphis, TN

Mary Shago

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto

Andrew J. Carroll

Department of Genetics, University of Alabama at Birmingham, Birmingham

Nyla A. Heerema

Julie M. Gastier-Foster

Brent L. Wood

Department of Pathology and Laboratory Medicine, Children’s Hospital of Los Angeles, Los Angeles

Lauren Sanclemente

Elizabeth A. Raetz

Department of Pediatrics and Perlmutter Cancer Center, NYU Langone Health, New York

Stephen P. Hunger

Department of Pediatrics and the Center for Childhood Cancer Research, Children’s Hospital of Philadelphia, Philadelphia

Mignon L. Loh

Seattle Children’s Hospital, Seattle

Eleanor Feingold

Tracie C. Rosser

Emily G. Allen

Stephanie L. Sherman

Karen R. Rabin

Philip J. Lupo

Jun J. Yang

Department of Pharmacy and Pharmaceutical Sciences