In silico-driven identification of potent CDK9 inhibitors through bioisosteric replacement and multi-stage virtual screening

Juliana Amorim; Luis Altamirano; Denise Silva de Souza; Chen Li; Syeda Abida Ejaz; Juan Carpio Arévalo

doi:10.1038/s41598-025-31230-8

In silico-driven identification of potent CDK9 inhibitors through bioisosteric replacement and multi-stage virtual screening

J Juliana Amorim L Luis Altamirano D Denise Silva de Souza C Chen Li (Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, USA.) S Syeda Abida Ejaz J Juan Carpio Arévalo

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Article Details

Journal Scientific Reports

Volume / Issue Vol. 16, Issue 1

Published December 11, 2025

DOI 10.1038/s41598-025-31230-8

ISSN 2045-2322

Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (6)

J

Juliana Amorim

L

Luis Altamirano

D

Denise Silva de Souza

C

Chen Li

Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, USA.

S

Syeda Abida Ejaz

J

Juan Carpio Arévalo

In silico-driven identification of potent CDK9 inhibitors through bioisosteric replacement and multi-stage virtual screening

Article Details

Journal Info

Authors (6)

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