Improvement in the potency of a N1-methylpseudouridine-modified self-amplifying RNA through mutations in the RNA-dependent RNA polymerase

Verónica Quintana; Josefina Caillava; Laura A. Byk; Juan A. Mondotte; Leandro Battini; Prutha Tarte; Marcelo M. Samsa; Claudia V. Filomatori; Diego E. Alvarez

doi:10.1016/j.jbc.2025.110487

Improvement in the potency of a N1-methylpseudouridine-modified self-amplifying RNA through mutations in the RNA-dependent RNA polymerase

V Verónica Quintana J Josefina Caillava L Laura A. Byk J Juan A. Mondotte L Leandro Battini P Prutha Tarte M Marcelo M. Samsa C Claudia V. Filomatori D Diego E. Alvarez

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Article Details

Journal Journal of Biological Chemistry

Volume / Issue Vol. 301, Issue 8

Published August 01, 2025

Pages 110487

DOI 10.1016/j.jbc.2025.110487

ISSN 0021-9258

Publisher Elsevier BV

Journal Info

Journal of Biological Chemistry

Elsevier BV

ISSN: 0021-9258 Open Access Life Sciences

Authors (9)

V

Verónica Quintana

J

Josefina Caillava

L

Laura A. Byk

J

Juan A. Mondotte

L

Leandro Battini

P

Prutha Tarte

M

Marcelo M. Samsa

C

Claudia V. Filomatori

D

Diego E. Alvarez

Improvement in the potency of a N1-methylpseudouridine-modified self-amplifying RNA through mutations in the RNA-dependent RNA polymerase

Article Details

Journal Info

Authors (9)

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