Improved protein binder design using β-pairing targeted RFdiffusion

I Isaac Sappington M Martin Toul D David S. Lee S Stephanie A. Robinson I Inna Goreshnik C Clara McCurdy T Tung Ching Chan N Nic Buchholz B Buwei Huang D Dionne Vafeados M Mariana Garcia-Sanchez N Nicole Roullier (Institute for Protein Design, University of Washington, Seattle, WA, USA.) M Matthias Glögl (Department of Biochemistry, University of Washington) C Christopher J. Kim (Department of Chemistry and Chemical Biology, Baker Laboratory) J Joseph L. Watson S Susana Vázquez Torres K Koen H. G. Verschueren K Kenneth Verstraete C Cynthia S. Hinck M Melisa Benard-Valle B Brian Coventry J Jeremiah Nelson Sims G Green Ahn X Xinru Wang A Andrew P. Hinck T Timothy P. Jenkins H Hannele Ruohola-Baker S Steven M. Banik S Savvas N. Savvides D David Baker

Article Details

Volume / Issue Vol. 17, Issue 1
Published January 10, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (30)

I

Isaac Sappington

M

Martin Toul

D

David S. Lee

S

Stephanie A. Robinson

I

Inna Goreshnik

C

Clara McCurdy

T

Tung Ching Chan

N

Nic Buchholz

B

Buwei Huang

D

Dionne Vafeados

M

Mariana Garcia-Sanchez

N

Nicole Roullier

Institute for Protein Design, University of Washington, Seattle, WA, USA.

M

Matthias Glögl

Department of Biochemistry, University of Washington

C

Christopher J. Kim

Department of Chemistry and Chemical Biology, Baker Laboratory

J

Joseph L. Watson

S

Susana Vázquez Torres

K

Koen H. G. Verschueren

K

Kenneth Verstraete

C

Cynthia S. Hinck

M

Melisa Benard-Valle

B

Brian Coventry

J

Jeremiah Nelson Sims

G

Green Ahn

X

Xinru Wang

A

Andrew P. Hinck

T

Timothy P. Jenkins

H

Hannele Ruohola-Baker

S

Steven M. Banik

S

Savvas N. Savvides

D

David Baker