Identifying daily-living features related to loneliness: A causal machine learning approach

Y Yuning Wang (Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang 110016, China) J Jennifer Auxier M Mark Amayag I Iman Azimi A Amir M. Rahmani P Pasi Liljeberg A Anna Axelin

Abstract

Background Loneliness is a distressing feeling that influences well-being. Immigrants’ experience of acculturation to a new dominant culture places them at risk for maladaptive behaviors and daily rhythms leading to loneliness. Identifying daily-living features that causally influence loneliness is essential for developing effective preventive mental health screening. Objective To identify the important daily living-features related to loneliness for the development of robust screening solutions using causal machine learning for health providers working with first-generation immigrants. Methods We monitored 39 immigrants in Finland for 28 days using mobile devices and wearables under free-living conditions. Data included ecological momentary assessments of loneliness, social interactions, physical activity, sleep, and cardiac features. We estimated the average treatment effect (ATE) of each daily-living feature (treatment variable) on loneliness scores (outcome) and validated the robustness of causal estimates using three refutation techniques. Results Our results reveal the ATE of various daily-living features on loneliness. Features such as longer outgoing call durations (ATE = 0.197, p < 0.001), higher LF/HF ratio (ATE = 0.129, p < 0.0001), higher respiratory rate (ATE = 0.144, p < 0.001), and increased inactivity (ATE = 0.130, p < 0.001) causally increased loneliness. Conversely, certain features exhibit negative ATEs, such as higher activity calories (ATE = −0.174, p < 0.001), sleep RMSSD (ATE = −0.128, p < 0.001), longer home duration (ATE = −0.107, p < 0.001), and more sleep time (ATE = −0.103, p < 0.001) mitigated loneliness. Conclusions Daily-living features, including social interactions, activity, sleep, and cardiac features, causally influence loneliness. Our findings provide a basis for loneliness screening targeting immigrant populations. Future work should refine the measurement and incorporate contextual information to establish more reliable causal links in real life.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 20, Issue 12
Published December 17, 2025
Pages e0336287
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (7)

Y

Yuning Wang

Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, 72 Wenhua Road, Shenyang 110016, China

J

Jennifer Auxier

M

Mark Amayag

I

Iman Azimi

A

Amir M. Rahmani

P

Pasi Liljeberg

A

Anna Axelin