Hydrogen–Deuterium Exchange Mass Spectrometry Reveals an Antibody-Induced Allosteric Pathway Driving SARS-CoV-2 Spike Trimer Disassembly

Y Yuxiang Luo B Banghui Liu (State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health) R Ruijie Liu (School of Pharmaceutical Sciences, Sun Yat-sen University, No. 132 Wai Huan Dong Lu, Guangzhou Higher Education Mega Center, Guangzhou 510006, China) Q Qiuluan Chen (Bioland Lab) X Xiaoli Xiong H Huilin Li

Article Details

Volume / Issue Vol. 148, Issue 10
Published March 18, 2026
Pages 10506-10521
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (6)

Y

Yuxiang Luo

B

Banghui Liu

State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health

R

Ruijie Liu

School of Pharmaceutical Sciences, Sun Yat-sen University, No. 132 Wai Huan Dong Lu, Guangzhou Higher Education Mega Center, Guangzhou 510006, China

Q

Qiuluan Chen

Bioland Lab

X

Xiaoli Xiong

H

Huilin Li