Human herpesvirus 6 viremia and encephalitis in CAR T-cell recipients
Abstract
Abstract Human herpesvirus 6 reactivation in chimeric antigen receptor T-cell recipients is reported to be rare. Our patient cohort (n = 119) experienced a sevenfold higher incidence of viremia than a previous study and 2 cases of encephalitis. Further studies are needed to determine risk factors for infection.
Article Details
Authors (6)
Stephanie T. Isaac
1Blood Transplant and Cell Therapies Program, Department of Haematology, Westmead Hospital, Westmead, NSW, Australia
David C. Bishop
1Blood Transplant and Cell Therapies Program, Department of Haematology, Westmead Hospital, Westmead, NSW, Australia
Fahad Shaikh
Mercy St. Vincent Medical Center, Toledo, Ohio, United States
Kenneth Micklethwaite
1Blood Transplant and Cell Therapies Program, Department of Haematology, Westmead Hospital, Westmead, NSW, Australia
David J. Gottlieb
Blood Transplant and Cell Therapies Program, Westmead Hospital, Sydney
Emily Blyth
5Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia