Homologative 1,3‐Functionalization of Alkenes via an Iodomethyl Thianthrenium Reagent

Abstract

Abstract Despite tremendous progress in alkene 1,2‐difunctionalization, analogous methods to generate 1,3‐patterns from alkenes remain limited. Recently, Silvi and co‐workers reported a homologative strategy to transform alkenes into 1,3‐dielectrophiles (DOI: https://doi.org/10.1002/anov.70005 ). They introduce a novel iodomethyl thianthrenium salt as a precursor to methyl thianthrenium radical, which adds across unactivated alkenes. Substitution of the 1,3‐dielectrophiles delivers a general homologative alkene difunctionalization platform.