Histone lactylation promotes rheumatoid arthritis progression by increasing NFATc2 expression and the production of anti-lactylated histone autoantibodies

G Gan Wu C Chenglin Yang Y Yuan Huang B Bin Liu H Haige Zhai Z Zelin Cao (Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Provincial Research Center for Basic Biological Sciences, College of Life Science and Technology, Huazhong University of Science and Technology) S Siyue Lu J Jijian Ji X Xinyue Yin X Xianming Xin S Shengwei Jin Y Youzhi Cai (Department of Orthopedics and Center for Sport Medicine, The First Affiliated Hospital, College of Medicine Zhejiang University) J Jianguang Wang

Article Details

Volume / Issue Vol. 16, Issue 1
Published October 10, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (13)

G

Gan Wu

C

Chenglin Yang

Y

Yuan Huang

B

Bin Liu

H

Haige Zhai

Z

Zelin Cao

Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Provincial Research Center for Basic Biological Sciences, College of Life Science and Technology, Huazhong University of Science and Technology

S

Siyue Lu

J

Jijian Ji

X

Xinyue Yin

X

Xianming Xin

S

Shengwei Jin

Y

Youzhi Cai

Department of Orthopedics and Center for Sport Medicine, The First Affiliated Hospital, College of Medicine Zhejiang University

J

Jianguang Wang