Heterochiral and Heterotypic Self-Assembly of Intrinsically Disordered Peptides Confers Peptide Supercoils with Exceptional Proteolytic Stability

Y Yuchen Qiao (Department of Chemistry) M Myeonggon Park (Martin A. Fisher School of Physics) M Matthew Chu (Department of Chemistry, Brandeis University, 415 South St., Waltham, Massachusetts 02453, United States) G Grace Wu (Department of Chemistry, Brandeis University, 415 South St., Waltham, Massachusetts 02453, United States) R Ruipeng Guo (Department of Electrical and Computer Engineering) C Chen Liu H Hongjian He (Department of Chemistry, Brandeis University, 415 South St., Waltham, Massachusetts 02453, United States) T Tongyu Li (Department of Electrical and Computer Engineering) L Lei Tian (Department of Electrical and Computer Engineering) X Xixiang Zhang (Material Science and Engineering Program, Division of Physical Science and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia.) W W. Benjamin Rogers (Martin A. Fisher School of Physics) B Bing Xu

Article Details

Volume / Issue Vol. 147, Issue 44
Published November 05, 2025
Pages 40727-40738
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (12)

Y

Yuchen Qiao

Department of Chemistry

M

Myeonggon Park

Martin A. Fisher School of Physics

M

Matthew Chu

Department of Chemistry, Brandeis University, 415 South St., Waltham, Massachusetts 02453, United States

G

Grace Wu

Department of Chemistry, Brandeis University, 415 South St., Waltham, Massachusetts 02453, United States

R

Ruipeng Guo

Department of Electrical and Computer Engineering

C

Chen Liu

H

Hongjian He

Department of Chemistry, Brandeis University, 415 South St., Waltham, Massachusetts 02453, United States

T

Tongyu Li

Department of Electrical and Computer Engineering

L

Lei Tian

Department of Electrical and Computer Engineering

X

Xixiang Zhang

Material Science and Engineering Program, Division of Physical Science and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia.

W

W. Benjamin Rogers

Martin A. Fisher School of Physics

B

Bing Xu