Hesperetin reduces neuronal death in an SHSY5Y Alzheimer’s model by inhibiting inflammation and apoptosis and pyroptosis cell death pathways

Leila Shafiee; Maryam Sadat Pishva; Rosa Hosseinzadegsn; Zahra Bahadori; Payam Baziyar; Mahtab Mehboodi; Samereh Khademee; Mohammadarian Akbari; Mahsa Motamed; Elham Nadimi

doi:10.1038/s41598-025-25777-9

Hesperetin reduces neuronal death in an SHSY5Y Alzheimer’s model by inhibiting inflammation and apoptosis and pyroptosis cell death pathways

L Leila Shafiee M Maryam Sadat Pishva R Rosa Hosseinzadegsn Z Zahra Bahadori P Payam Baziyar M Mahtab Mehboodi S Samereh Khademee M Mohammadarian Akbari M Mahsa Motamed E Elham Nadimi

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Article Details

Journal Scientific Reports

Volume / Issue Vol. 15, Issue 1

Published November 25, 2025

DOI 10.1038/s41598-025-25777-9

ISSN 2045-2322

Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (10)

L

Leila Shafiee

M

Maryam Sadat Pishva

R

Rosa Hosseinzadegsn

Z

Zahra Bahadori

P

Payam Baziyar

M

Mahtab Mehboodi

S

Samereh Khademee

M

Mohammadarian Akbari

M

Mahsa Motamed

E

Elham Nadimi

Hesperetin reduces neuronal death in an SHSY5Y Alzheimer’s model by inhibiting inflammation and apoptosis and pyroptosis cell death pathways

Article Details

Journal Info

Authors (10)

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