Harnessing Electrochemistry for Direct Deoxygenative Silylation of Alcohols and Ketones
Abstract
AbstractAlcohols and ketones are abundant and structurally diverse feedstocks, yet their direct transformation into organosilicon compounds remains challenging due to the difficulty in selective cleaving C─OH and C═O bonds. Here, we report an electrochemically driven deoxygenative C─Si bond formation strategy that converts alcohols and ketones directly to organosilicon compounds. The reactions operate under mild conditions without external redox reagents and sacrificial electrodes. A wide range of alcohols, including primary, secondary, and tertiary alcohols, as well as ketones, are efficiently converted to the corresponding organosilane products. Overall, this study provides a step‐economical, highly efficient, and synthetically versatile platform for the direct conversion of feedstock chemicals into valuable organosilicon compounds.
Article Details
Authors (5)
Yi‐Xian Zheng
State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, and College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China
Yuan‐Xin Wu
State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, and College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China
Li‐Jian Su
State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, and College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China
Peng Xiong
Hai‐Chao Xu
State Key Laboratory of Physical Chemistry of Solid Surfaces Fujian Key Laboratory of Chemical Biology and College of Chemistry and Chemical Engineering Xiamen University Xiamen China