Gut microbiota-induced perturbation in bile acids alter keratinocyte lipid metabolism via FXR-NQO1 signaling in psoriasis

Panpan Lian; Renwei Lu; Chaode Gu; Junaid Wazir; Wentong Wang; Yangyongyi Zong; Yun Xia; Jie Ni; Huimei Chen; Enrico Petretto; Eckardt Treuter; Rongrong Fan; Airong Yang; Zhonglan Su; Hongwei Wang; Zhiqiang Huang

doi:10.1038/s41467-026-72417-5

Gut microbiota-induced perturbation in bile acids alter keratinocyte lipid metabolism via FXR-NQO1 signaling in psoriasis

P Panpan Lian R Renwei Lu C Chaode Gu J Junaid Wazir W Wentong Wang Y Yangyongyi Zong Y Yun Xia J Jie Ni H Huimei Chen E Enrico Petretto E Eckardt Treuter R Rongrong Fan A Airong Yang Z Zhonglan Su H Hongwei Wang (School of Physics and Laboratory of Zhongyuan Light) Z Zhiqiang Huang (Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering)

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published May 18, 2026

DOI 10.1038/s41467-026-72417-5

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (16)

P

Panpan Lian

R

Renwei Lu

C

Chaode Gu

J

Junaid Wazir

W

Wentong Wang

Y

Yangyongyi Zong

Y

Yun Xia

J

Jie Ni

H

Huimei Chen

E

Enrico Petretto

E

Eckardt Treuter

R

Rongrong Fan

A

Airong Yang

Z

Zhonglan Su

H

Hongwei Wang

School of Physics and Laboratory of Zhongyuan Light

Z

Zhiqiang Huang

Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering

Gut microbiota-induced perturbation in bile acids alter keratinocyte lipid metabolism via FXR-NQO1 signaling in psoriasis

Article Details

Journal Info

Authors (16)

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