Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations

J Joshua S. Weinstock (Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.) S Sharjeel A. Chaudhry M Maria Ioannou M Maria Viskadourou P Paula Reventun Y Yasminka A. Jakubek L L. Alexander Liggett C Cecelia Laurie (University of Washington, Seattle, WA, USA.) J Jai G. Broome A Alyna Khan (University of Washington, Seattle, WA, USA.) K Kent D. Taylor (The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.) X Xiuqing Guo P Patricia A. Peyser E Eric Boerwinkle N Nathalie Chami E Eimear E. Kenny R Ruth J. Loos B Bruce M. Psaty J Jennifer A. Brody J Jeong H. Yun (Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School) M Michael H. Cho (Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA.) R Ramachandran S. Vasan (Framingham Heart Study, National Heart, Lung, and Blood Institute, National Institutes of Health and Boston University, Framingham, MA, USA.) S Sharon L. Kardia J Jennifer A. Smith L Laura M. Raffield (Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.) A Aurelian Bidulescu E Emily C. O’Brien M Mariza de Andrade J Jerome I. Rotter S Stephen S. Rich (Department of Genome Sciences, School of Medicine, University of Virginia, Charlottesville, VA, USA.) R Russell P. Tracy (Laboratory for Clinical Biochemistry Research, Larner College of Medicine, University of Vermont, Burlington, VT, USA.) Y Yii Der Ida Chen C C. Charles. Gu C Chao A. Hsiung (Institute of Population Health Sciences, National Health Research Institutes) C Charles Kooperberg (Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.) B Bernhard Haring R Rami Nassir R Rasika Mathias A Alex Reiner (Department of Epidemiology, University of Washington, Seattle, WA, USA.) V Vijay G. Sankaran C Charles J. Lowenstein T Thomas W. Blackwell (Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.) G Goncalo R. Abecasis A Albert V. Smith (Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.) H Hyun M. Kang P Pradeep Natarajan S Siddhartha Jaiswal A Alexander Bick W Wendy S. Post P Paul Scheet P Paul Auer (Medical College of Wisconsin, Milwaukee, WI, USA.) T Theodoros Karantanos A Alexis Battle M Marios Arvanitis

Article Details

Volume / Issue Vol. 16, Issue 1
Published October 16, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (54)

J

Joshua S. Weinstock

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.

S

Sharjeel A. Chaudhry

M

Maria Ioannou

M

Maria Viskadourou

P

Paula Reventun

Y

Yasminka A. Jakubek

L

L. Alexander Liggett

C

Cecelia Laurie

University of Washington, Seattle, WA, USA.

J

Jai G. Broome

A

Alyna Khan

University of Washington, Seattle, WA, USA.

K

Kent D. Taylor

The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.

X

Xiuqing Guo

P

Patricia A. Peyser

E

Eric Boerwinkle

N

Nathalie Chami

E

Eimear E. Kenny

R

Ruth J. Loos

B

Bruce M. Psaty

J

Jennifer A. Brody

J

Jeong H. Yun

Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School

M

Michael H. Cho

Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA.

R

Ramachandran S. Vasan

Framingham Heart Study, National Heart, Lung, and Blood Institute, National Institutes of Health and Boston University, Framingham, MA, USA.

S

Sharon L. Kardia

J

Jennifer A. Smith

L

Laura M. Raffield

Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

A

Aurelian Bidulescu

E

Emily C. O’Brien

M

Mariza de Andrade

J

Jerome I. Rotter

S

Stephen S. Rich

Department of Genome Sciences, School of Medicine, University of Virginia, Charlottesville, VA, USA.

R

Russell P. Tracy

Laboratory for Clinical Biochemistry Research, Larner College of Medicine, University of Vermont, Burlington, VT, USA.

Y

Yii Der Ida Chen

C

C. Charles. Gu

C

Chao A. Hsiung

Institute of Population Health Sciences, National Health Research Institutes

C

Charles Kooperberg

Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA.

B

Bernhard Haring

R

Rami Nassir

R

Rasika Mathias

A

Alex Reiner

Department of Epidemiology, University of Washington, Seattle, WA, USA.

V

Vijay G. Sankaran

C

Charles J. Lowenstein

T

Thomas W. Blackwell

Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.

G

Goncalo R. Abecasis

A

Albert V. Smith

Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.

H

Hyun M. Kang

P

Pradeep Natarajan

S

Siddhartha Jaiswal

A

Alexander Bick

W

Wendy S. Post

P

Paul Scheet

P

Paul Auer

Medical College of Wisconsin, Milwaukee, WI, USA.

T

Theodoros Karantanos

A

Alexis Battle

M

Marios Arvanitis