GCN5 drives MASLD progression through LXRα/SREBP1c signaling pathway–mediated de novo lipogenesis

H Hai-Tao Xiao P Peng Song (Institute of Multidisciplinary Research for Advanced Materials, Tohoku University2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan) J Jing Jin Y Yong-Dan Wang Y Yin-Yue Xu H He Wu X Xue-Xue Shao Q Qi-Feng Gan J Jian He (Department of Chemistry) Y Yan-Rong Wen J Jing Zhu (Hefei National Research Center for Physical Sciences at the Microscale, CAS Key Laboratory of Strongly-Coupled Quantum Matter Physics, Key Laboratory of Surface and Interface Chemistry and Energy Catalysis of Anhui Higher Education Institutes, Department of Chemical Physics) B Bao-Yi Chen P Ping Zhou L Li-Na Lai H Hua Yang (State Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, China) P Ping Li Z Zu-Guo Zheng

Article Details

Volume / Issue Vol. 17, Issue 1
Published February 16, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (17)

H

Hai-Tao Xiao

P

Peng Song

Institute of Multidisciplinary Research for Advanced Materials, Tohoku University2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577, Japan

J

Jing Jin

Y

Yong-Dan Wang

Y

Yin-Yue Xu

H

He Wu

X

Xue-Xue Shao

Q

Qi-Feng Gan

J

Jian He

Department of Chemistry

Y

Yan-Rong Wen

J

Jing Zhu

Hefei National Research Center for Physical Sciences at the Microscale, CAS Key Laboratory of Strongly-Coupled Quantum Matter Physics, Key Laboratory of Surface and Interface Chemistry and Energy Catalysis of Anhui Higher Education Institutes, Department of Chemical Physics

B

Bao-Yi Chen

P

Ping Zhou

L

Li-Na Lai

H

Hua Yang

State Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, China

P

Ping Li

Z

Zu-Guo Zheng