Gastric ultrasound reveals no association between prolonged fasting duration and gastric residual volume in pediatric patients

Q Qingda Wu B Bin Liu Z Zhouwu Wang L Lingzhi Chen H Hao Liu Q Qi Zou (Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Institute of Fine Chemicals, School of Chemistry and Molecular Engineering) Y Yongzhen Zhao Z Zhenhao Ding L Lu Chen Z Zhenwei Zheng

Abstract

Abstract Prolonged preoperative fasting is common in pediatric anesthesia, yet its effect on gastric residual volume (GRV) remains inadequately explored. We conducted a prospective cross-sectional study to examine the association between prolonged fasting duration and GRV measured using point-of-care gastric ultrasonography. A total of 491 children aged 1–12 years scheduled for elective surgery under general anesthesia after fasting more than 8 h were included. GRV was measured using point-of-care gastric ultrasonography and calculated using a validated formula, then normalized to body weight. The primary endpoint was the association between fasting duration and weight-adjusted GRV (GRV/WT). Among the participants (median age 89 months; 308 boys), fifteen patients (3.05%) had a stomach at risk of aspiration (GRV/WT > 1.25 mL kg −1 ) and 29 (5.91%) showed high-risk gastric antrum morphology. Spearman correlation analysis demonstrated no significant association between prolonged fasting duration and GRV/WT (ρ = 0.037, 95% CI: − 0.054 to 0.128, p  = 0.41). GRV/WT correlated positively with age and negatively with body mass index. These findings suggest that prolonged preoperative fasting does not independently associate with GRV in pediatric patients.

Article Details

Volume / Issue Vol. 1, Issue 1
Published June 26, 2026
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (10)

Q

Qingda Wu

B

Bin Liu

Z

Zhouwu Wang

L

Lingzhi Chen

H

Hao Liu

Q

Qi Zou

Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Institute of Fine Chemicals, School of Chemistry and Molecular Engineering

Y

Yongzhen Zhao

Z

Zhenhao Ding

L

Lu Chen

Z

Zhenwei Zheng