Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function

M Marta Barisa H Henrike P. Muller E Elisa Zappa R Rivani Shah J Juliane L. Buhl B Benjamin Draper C Courtney Himsworth C Chantelle Bowers S Sophie Munnings-Tomes M Marilena Nicolaidou S Sonia Morlando K Kathleen Birley C Clara Leboreiro-Babe A Alice Vitali L Laura Privitera K Kyle O’Sullivan A Ailsa Greppi M Magdalena Buschhaus M Mario Barrera Román S Sam de Blank F Femke van den Ham B Brenna R. van ‘t Veld G Gabrielle Ferry J Jonathan Fisher D Debarati Shome R Reza Nadafi I Israrul H. Ansari R Rogier Reijmers S Stefano Giuliani P Paul Sondel L Laura K. Donovan L Louis Chesler J Jan Molenaar J Jarno Drost A Anne C. Rios K Kerry Chester J Judith Wienke J John Anderson (Google Research)