Fluorogenic Platform for Real-Time Imaging of Subcellular Payload Release in Antibody–Drug Conjugates

F Ferran Nadal-Bufi (Centre for Inflammation Research) P Paulin L. Salomon (AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States) F Fabio de Moliner (Centre for Inflammation Research) K Kathy A. Sarris (AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States) Z Zhi Wang (School of Chemistry and Chemical Engineering, State Key Laboratory of Crystal Materials) R Rachel D. Wills (AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States) V Violeta L. Marin (AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States) X Xiaona Shi (WuXi AppTec, 168 Nanhai Road, Tianjin Economic-Technological Development Area TEDA, Tianjin 300457, China) K Kuo Zhou (WuXi AppTec, 168 Nanhai Road, Tianjin Economic-Technological Development Area TEDA, Tianjin 300457, China) Z Zhongyuan Wang Z Zhou Xu (Monash Centre for Electron Microscopy) M Michael J. McPherson (AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States) C Christopher C. Marvin (AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States) A Adrian D. Hobson (AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States) M Marc Vendrell (Centre for Inflammation Research)

Article Details

Volume / Issue Vol. 147, Issue 9
Published March 05, 2025
Pages 7578-7587
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (15)

F

Ferran Nadal-Bufi

Centre for Inflammation Research

P

Paulin L. Salomon

AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States

F

Fabio de Moliner

Centre for Inflammation Research

K

Kathy A. Sarris

AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States

Z

Zhi Wang

School of Chemistry and Chemical Engineering, State Key Laboratory of Crystal Materials

R

Rachel D. Wills

AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States

V

Violeta L. Marin

AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States

X

Xiaona Shi

WuXi AppTec, 168 Nanhai Road, Tianjin Economic-Technological Development Area TEDA, Tianjin 300457, China

K

Kuo Zhou

WuXi AppTec, 168 Nanhai Road, Tianjin Economic-Technological Development Area TEDA, Tianjin 300457, China

Z

Zhongyuan Wang

Z

Zhou Xu

Monash Centre for Electron Microscopy

M

Michael J. McPherson

AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States

C

Christopher C. Marvin

AbbVie Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States

A

Adrian D. Hobson

AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States

M

Marc Vendrell

Centre for Inflammation Research