Exosome engineered upconversion nanoparticles with targeting moieties enhance Aβ aggregate clearance and mitigate neurotoxicity in Alzheimer’s disease

C Chen Jin (State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences) Z Zhihao Ma P Peipei Wu (Cold Spring Harbor Laboratory) H Hui Qian L Lin Su (Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.) Z Zhiqiang Zhu (State Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering) J Jie Wang (State Key Laboratory of Molecular Oncology, Beijing Key Laboratory, CAMS Key Laboratory of Translational Research on Lung Cancer, Department of Medical Oncology Cancer Hospital, Chinese Academy of Medical Sciences Beijing China)

Article Details

Volume / Issue Vol. 15, Issue 1
Published November 18, 2025
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (7)

C

Chen Jin

State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences

Z

Zhihao Ma

P

Peipei Wu

Cold Spring Harbor Laboratory

H

Hui Qian

L

Lin Su

Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.

Z

Zhiqiang Zhu

State Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering

J

Jie Wang

State Key Laboratory of Molecular Oncology, Beijing Key Laboratory, CAMS Key Laboratory of Translational Research on Lung Cancer, Department of Medical Oncology Cancer Hospital, Chinese Academy of Medical Sciences Beijing China