Evidence supporting a catalytic pentad mechanism for the proteasome and other N-terminal nucleophile enzymes

D Darlene Fung (Department of Pathology, Harvard Medical School and Brigham and Women’s Hospital) A Aida Razi M Michael Pandos B Benjamin Velez (Department of Pathology, Harvard Medical School and Brigham and Women’s Hospital) E Erignacio Fermin Perez (Department of Pathology, Harvard Medical School and Brigham and Women’s Hospital) L Lea Adams S Shaun Rawson (Harvard Cryo-Electron Microscopy Center for Structural Biology, Harvard Medical School) R Richard M. Walsh (Harvard Cryo-Electron Microscopy Center for Structural Biology, Harvard Medical School) J John Hanna

Article Details

Volume / Issue Vol. 16, Issue 1
Published March 26, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (9)

D

Darlene Fung

Department of Pathology, Harvard Medical School and Brigham and Women’s Hospital

A

Aida Razi

M

Michael Pandos

B

Benjamin Velez

Department of Pathology, Harvard Medical School and Brigham and Women’s Hospital

E

Erignacio Fermin Perez

Department of Pathology, Harvard Medical School and Brigham and Women’s Hospital

L

Lea Adams

S

Shaun Rawson

Harvard Cryo-Electron Microscopy Center for Structural Biology, Harvard Medical School

R

Richard M. Walsh

Harvard Cryo-Electron Microscopy Center for Structural Biology, Harvard Medical School

J

John Hanna