ERAD-level gene switches for on-demand protein secretion and rapidly controlled gene therapies

T Ting Gao (Key Laboratory of Functional Inorganic Material Chemistry, Ministry of Education; School of Chemistry and Materials Science) S Shichao Li Y Yuxuan Fan W Wenyi Yan M Minghui He (College of Chemistry and Molecular Sciences) Q Qihao Zhang (State Key Laboratory of Synthetic Chemistry, Shanghai Hong Kong Joint Laboratory in Chemical Synthesis, Department of Chemistry) Y Yilin Li Q Qi Liu P Pengli Wang J Jian Jiang (Department of Materials Science & Engineering) L Lihang Zhang Y Yuting Zhou (Department of Chemistry) L Liuqi Zhao Q Qiqi Xiong Y Yuhang Wu S Sichen Yuan (Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison) S Shaocong Fang H Hongyun Tang (School of Life Sciences, Westlake University) M Martin Fussenegger H Hui Wang J Jiawei Shao (Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore) M Mingqi Xie

Article Details

Volume / Issue Vol. 1, Issue 1
Published July 30, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (22)

T

Ting Gao

Key Laboratory of Functional Inorganic Material Chemistry, Ministry of Education; School of Chemistry and Materials Science

S

Shichao Li

Y

Yuxuan Fan

W

Wenyi Yan

M

Minghui He

College of Chemistry and Molecular Sciences

Q

Qihao Zhang

State Key Laboratory of Synthetic Chemistry, Shanghai Hong Kong Joint Laboratory in Chemical Synthesis, Department of Chemistry

Y

Yilin Li

Q

Qi Liu

P

Pengli Wang

J

Jian Jiang

Department of Materials Science & Engineering

L

Lihang Zhang

Y

Yuting Zhou

Department of Chemistry

L

Liuqi Zhao

Q

Qiqi Xiong

Y

Yuhang Wu

S

Sichen Yuan

Pharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison

S

Shaocong Fang

H

Hongyun Tang

School of Life Sciences, Westlake University

M

Martin Fussenegger

H

Hui Wang

J

Jiawei Shao

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore

M

Mingqi Xie