Enzyme-Triggered Self-Immobilization of an NIR Prodrug for Tumor-Selective Cancer Vaccination

Y Yuyao Li (Materdicine Lab, School of Life Sciences) H Hongze Ren (Materdicine Lab, School of Life Sciences) J Jiayi Feng (Materdicine Lab, School of Life Sciences) X Xiaochuan Shan (Department of Medical Ultrasound) C Chaoying Zhang (State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of New Drug Design, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Pharmacy) J Jin Nan (Department of Radiology, Huashan Hospital, State Key Laboratory of Medical Neurobiology, National Center for Neurological Disorders) Z Zhengqi Tang (Materdicine Lab, School of Life Sciences) X Xueqin Ding (Materdicine Lab, School of Life Sciences) M Meihua Yu (Materdicine Lab, School of Life Sciences) H Hexin Xie (State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of New Drug Design, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Pharmacy) Y Yu Chen

Article Details

Volume / Issue Vol. 148, Issue 15
Published April 22, 2026
Pages 15655-15671
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (11)

Y

Yuyao Li

Materdicine Lab, School of Life Sciences

H

Hongze Ren

Materdicine Lab, School of Life Sciences

J

Jiayi Feng

Materdicine Lab, School of Life Sciences

X

Xiaochuan Shan

Department of Medical Ultrasound

C

Chaoying Zhang

State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of New Drug Design, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Pharmacy

J

Jin Nan

Department of Radiology, Huashan Hospital, State Key Laboratory of Medical Neurobiology, National Center for Neurological Disorders

Z

Zhengqi Tang

Materdicine Lab, School of Life Sciences

X

Xueqin Ding

Materdicine Lab, School of Life Sciences

M

Meihua Yu

Materdicine Lab, School of Life Sciences

H

Hexin Xie

State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of New Drug Design, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Pharmacy

Y

Yu Chen