Enhancing precision in lymphoma detection with novel deep transformer-based neural networks

T Turki M. Alanazi

Abstract

Lymphoma appears as swollen lymph nodes and weakened immune-protective tissues, frequently resulting in tiredness and loss of weight. Improving the outlook of this malignancy includes using computer-assisted analysis of Positron Emission Tomography (PET) pictures, which identify changes in metabolism. This article presents an Automatic Pre-Segmentation Model (APSM) that uses the Swin Transformer (ST). The APSM accurately separates inputs by recognizing pixel differences caused by changes in metabolism in various tissues and lymph nodes. Training the Swin Transformer system for classification and identification happens simultaneously, focusing mainly on the lymph node area. The model effectively divides the Lymphoma area by examining differences in patterns between regional features and changes in pixels. This segmentation model combines transformer network training to simultaneously learn fractal variations and feature changes, helping to adjust the relationships between training and testing inputs. The segmentation model’s effectiveness comes from its capability to stop training the matching transformer network when it identifies new deviations, alterations, or both. The proposed model achieved 12.68% higher segmentation accuracy, 13.38% improved precision, and reduced overhead, error, and segmentation time by 12.73%, 9.27%, and 10.23%, respectively, outperforming existing methods.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 20, Issue 8
Published August 13, 2025
Pages e0329261
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (1)

T

Turki M. Alanazi