Engineering biology applications for environmental solutions: potential and challenges

D David J. Lea-Smith F Francis Hassard F Frederic Coulon N Natalie Partridge L Louise Horsfall K Kyle D. J. Parker R Robert D. J. Smith R Ronan R. McCarthy B Boyd McKew T Tony Gutierrez V Vinod Kumar G Gabriella Dotro Z Zhugen Yang (Cranfield Water Science Institute, Cranfield University) T Thomas P. Curtis P Peter Golyshin S Sonia Heaven B Bruce Jefferson P Paul Jeffrey D Davey L. Jones K Kristell Le Corre Pidou Y Yongqiang Liu (Key Laboratory of Evolution & Marine Biodiversity (Ministry of Education) and Institute of Evolution & Marine Biodiversity, Ocean University of China) T Tao Lyu C Cindy Smith A Alexander Yakunin Y Yue Zhang N Natalio Krasnogor

Abstract

Abstract Engineering biology applies synthetic biology to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. This perspective outlines innovations in engineering biology, its integration with other technologies (e.g., nanotechnology, IoT, AI), and commercial ventures leveraging these advancements. We also discuss commercialisation and scaling challenges, biosafety and biosecurity considerations including biocontainment strategies, social and political dimensions, and governance issues that must be addressed for successful real-world implementation. Finally, we highlight future perspectives and propose strategies to overcome existing hurdles, aiming to accelerate the adoption of engineering biology for environmental solutions.

Article Details

Volume / Issue Vol. 16, Issue 1
Published April 14, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (26)

D

David J. Lea-Smith

F

Francis Hassard

F

Frederic Coulon

N

Natalie Partridge

L

Louise Horsfall

K

Kyle D. J. Parker

R

Robert D. J. Smith

R

Ronan R. McCarthy

B

Boyd McKew

T

Tony Gutierrez

V

Vinod Kumar

G

Gabriella Dotro

Z

Zhugen Yang

Cranfield Water Science Institute, Cranfield University

T

Thomas P. Curtis

P

Peter Golyshin

S

Sonia Heaven

B

Bruce Jefferson

P

Paul Jeffrey

D

Davey L. Jones

K

Kristell Le Corre Pidou

Y

Yongqiang Liu

Key Laboratory of Evolution & Marine Biodiversity (Ministry of Education) and Institute of Evolution & Marine Biodiversity, Ocean University of China

T

Tao Lyu

C

Cindy Smith

A

Alexander Yakunin

Y

Yue Zhang

N

Natalio Krasnogor