Engineering an Imine Reductase for Enantioselective Synthesis of Atropisomeric Amides

Z Zhouchang Yao (State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology) R Runze Meng (State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology) Z Zitian Zhou (State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology) L Luyao Yu (State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology) Z Zhiyun Wu (State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology) L Longqing Tang (State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology) T Tianzhang Qiao (Department of Chemistry and Chemical Biology) K Ke Li L Ling Huang D Danqing Song (State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology) H Haigen Fu (State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology)

Article Details

Volume / Issue Vol. 147, Issue 44
Published November 05, 2025
Pages 40616-40625
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (11)

Z

Zhouchang Yao

State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology

R

Runze Meng

State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology

Z

Zitian Zhou

State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology

L

Luyao Yu

State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology

Z

Zhiyun Wu

State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology

L

Longqing Tang

State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology

T

Tianzhang Qiao

Department of Chemistry and Chemical Biology

K

Ke Li

L

Ling Huang

D

Danqing Song

State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology

H

Haigen Fu

State Key Laboratory of Bioactive Substances and Function of Natural Medicines, Institute of Medicinal Biotechnology