Engineered Un1Cas12f1 for multiplex genome editing with enhanced activity and targeting scope

Y Yanan Huo J Jiale Mei D Dan Zhang (Laboratory of Inflammation and Vaccines, Shenzhen Institutes of Advanced Technology) B Bing Yan (Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences) D Dexin Zhang C Chao Dong S Shuming Yin M Meizhen Liu X Xinyan Wang D Dan Chen Y Yuting Guan G Gaojie Song B Bing Du Y Yongming Wang (State Key Laboratory of Synergistic Chem-Bio Synthesis, Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University) Z Zongli Zheng H Hong Liu D Dali Li L Lei Yang L Liren Wang

Article Details

Volume / Issue Vol. 17, Issue 1
Published February 19, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (19)

Y

Yanan Huo

J

Jiale Mei

D

Dan Zhang

Laboratory of Inflammation and Vaccines, Shenzhen Institutes of Advanced Technology

B

Bing Yan

Key Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences

D

Dexin Zhang

C

Chao Dong

S

Shuming Yin

M

Meizhen Liu

X

Xinyan Wang

D

Dan Chen

Y

Yuting Guan

G

Gaojie Song

B

Bing Du

Y

Yongming Wang

State Key Laboratory of Synergistic Chem-Bio Synthesis, Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University

Z

Zongli Zheng

H

Hong Liu

D

Dali Li

L

Lei Yang

L

Liren Wang