Endothelial IRE1α promotes thrombospondin-1 mRNA decay and supports metabolic stress adaptation of pancreatic islets

X Xiaoge Zhang S Shijia Huang P Peng Chen Z Ziyin Zhang J Jie Cai (National and Local Joint Engineering Research Center of MPTES in High Energy and Safety LIBs, Engineering Research Center of MTEES (Ministry of Education), Research Center of BMET (Guangdong Province), and Key Lab. of ETESPG(GHEI), School of Chemistry) T Ting Yu (Department of Chemistry, McGill University, 801 Sherbrooke Street W, Montréal, Quebec H3A 0B8, Canada) Z Zhixiong Xia S Shubo Yuan Y Yong Chen M Mengjuan Gao Z Zhuyin Wu J Jiongyi He Y Yifei Liao (Division of Infectious Diseases, Department of Medicine, Brigham and Women’s Hospital) Q Qi Fu Q Qiong Yang (State Key Laboratory of Vaccines for Infectious Diseases, Xiang-An Biomedicine Laboratory, Department of Laboratory Medicine, School of Public Health, Xiamen University) T Tailang Yin J Jie Liu K Ke Song S Sheng-Zhong Duan T Tao Yang L Liangyou Rui Y Yi Arial Zeng Z Zhuo-Xian Meng J Jianmiao Liu Y Yong Liu

Article Details

Volume / Issue Vol. 17, Issue 1
Published January 09, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (25)

X

Xiaoge Zhang

S

Shijia Huang

P

Peng Chen

Z

Ziyin Zhang

J

Jie Cai

National and Local Joint Engineering Research Center of MPTES in High Energy and Safety LIBs, Engineering Research Center of MTEES (Ministry of Education), Research Center of BMET (Guangdong Province), and Key Lab. of ETESPG(GHEI), School of Chemistry

T

Ting Yu

Department of Chemistry, McGill University, 801 Sherbrooke Street W, Montréal, Quebec H3A 0B8, Canada

Z

Zhixiong Xia

S

Shubo Yuan

Y

Yong Chen

M

Mengjuan Gao

Z

Zhuyin Wu

J

Jiongyi He

Y

Yifei Liao

Division of Infectious Diseases, Department of Medicine, Brigham and Women’s Hospital

Q

Qi Fu

Q

Qiong Yang

State Key Laboratory of Vaccines for Infectious Diseases, Xiang-An Biomedicine Laboratory, Department of Laboratory Medicine, School of Public Health, Xiamen University

T

Tailang Yin

J

Jie Liu

K

Ke Song

S

Sheng-Zhong Duan

T

Tao Yang

L

Liangyou Rui

Y

Yi Arial Zeng

Z

Zhuo-Xian Meng

J

Jianmiao Liu

Y

Yong Liu