Encapsulation of <sup>211</sup> At(Ø) <sup>+</sup> into a Nanoscale Covalent Organic Framework Prevents Deastatination In Vivo

L Linwei He (State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions) X Xijian Chen (Key Laboratory of Radiation Physics and Technology of the Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, No. 29, Wang Jiang Road, Sichuan Province, Chengdu 610064, China) Z Zhuowei Zhang (College of Chemistry) L Long Qiu (Key Laboratory of Radiation Physics and Technology of the Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, No. 29, Wang Jiang Road, Sichuan Province, Chengdu 610064, China) J Jie Lyu (Key Laboratory of Radiation Physics and Technology of the Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, No. 29, Wang Jiang Road, Sichuan Province, Chengdu 610064, China) R Ruitong Hou (Key Laboratory of Radiation Physics and Technology of the Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, No. 29, Wang Jiang Road, Sichuan Province, Chengdu 610064, China) L Lixi Chen (State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions) W Wenqi Zhang Z Zhonglin Ma (State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions) F Fuqiang Zhao (State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions) J Juan Diwu (State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions) N Ning Liu W Wei Chen L Long Chen (Department of Chemistry, Frontiers Science Center for New Organic Matter and State Key Laboratory of Advanced Chemical Power Sources, College of Chemistry) J Jing Su F Feize Li (Key Laboratory of Radiation Physics and Technology of the Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, No. 29, Wang Jiang Road, Sichuan Province, Chengdu 610064, China) Z Zhifang Chai S Shuao Wang (State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Biomedical Basic Research Center (BBRC) of Jiangsu)

Article Details

Volume / Issue Vol. 148, Issue 4
Published February 04, 2026
Pages 4074-4086
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (18)

L

Linwei He

State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions

X

Xijian Chen

Key Laboratory of Radiation Physics and Technology of the Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, No. 29, Wang Jiang Road, Sichuan Province, Chengdu 610064, China

Z

Zhuowei Zhang

College of Chemistry

L

Long Qiu

Key Laboratory of Radiation Physics and Technology of the Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, No. 29, Wang Jiang Road, Sichuan Province, Chengdu 610064, China

J

Jie Lyu

Key Laboratory of Radiation Physics and Technology of the Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, No. 29, Wang Jiang Road, Sichuan Province, Chengdu 610064, China

R

Ruitong Hou

Key Laboratory of Radiation Physics and Technology of the Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, No. 29, Wang Jiang Road, Sichuan Province, Chengdu 610064, China

L

Lixi Chen

State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions

W

Wenqi Zhang

Z

Zhonglin Ma

State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions

F

Fuqiang Zhao

State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions

J

Juan Diwu

State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions

N

Ning Liu

W

Wei Chen

L

Long Chen

Department of Chemistry, Frontiers Science Center for New Organic Matter and State Key Laboratory of Advanced Chemical Power Sources, College of Chemistry

J

Jing Su

F

Feize Li

Key Laboratory of Radiation Physics and Technology of the Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, No. 29, Wang Jiang Road, Sichuan Province, Chengdu 610064, China

Z

Zhifang Chai

S

Shuao Wang

State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Biomedical Basic Research Center (BBRC) of Jiangsu