Enantiodivergent Access to Acyclic Quaternary Stereocenters by Nitrilase-Catalyzed Desymmetrizing Hydrolysis of Malononitriles

Y Yong-Ze Xie (College of Chemistry and Molecular Sciences) D Dong-Sheng Yang (College of Chemistry and Molecular Sciences) L Li-Gang Bai (College of Chemistry and Molecular Sciences) J Jin-Wei Yang (College of Chemistry and Molecular Sciences) B Bo Gu (College of Chemistry and Molecular Sciences) M Meng-Ting Liu Q Qi-Yue Wang (School of Pharmacy) W Wang Wang W Wen-Bo Liu (Hubei Research Center of Fundamental Science-Chemistry, Engineering Research Center of Organosilicon Compounds & Materials (Ministry of Education), Hubei Key Lab on Organic and Polymeric Optoelectronic Materials, and College of Chemistry and Molecular Sciences) H Heng Song (College of Chemistry and Molecular Sciences)

Article Details

Volume / Issue Vol. 147, Issue 30
Published July 30, 2025
Pages 26980-26990
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (10)

Y

Yong-Ze Xie

College of Chemistry and Molecular Sciences

D

Dong-Sheng Yang

College of Chemistry and Molecular Sciences

L

Li-Gang Bai

College of Chemistry and Molecular Sciences

J

Jin-Wei Yang

College of Chemistry and Molecular Sciences

B

Bo Gu

College of Chemistry and Molecular Sciences

M

Meng-Ting Liu

Q

Qi-Yue Wang

School of Pharmacy

W

Wang Wang

W

Wen-Bo Liu

Hubei Research Center of Fundamental Science-Chemistry, Engineering Research Center of Organosilicon Compounds & Materials (Ministry of Education), Hubei Key Lab on Organic and Polymeric Optoelectronic Materials, and College of Chemistry and Molecular Sciences

H

Heng Song

College of Chemistry and Molecular Sciences