Electrochemical Deoxygenative Silylation of Alcohols
Abstract
Abstract Alcohols are highly common organic compounds but remain scarce as alkyl donors in synthetic procedures. Here, we describe an electrochemical procedure for their deoxygenative cross‐electrophile coupling with hydrosilanes, furnishing organosilane products in good to excellent yields. Mechanistic studies provide insights into the operating pathways of this semi‐paired electrolytic transformation, suggesting that silyl ethers are likely reaction intermediates. Furthermore, a unified mechanistic proposal is presented that accounts for observed reactivity differences with analogous deoxygenative electrocarboxylation.
Article Details
Authors (8)
Piret Villo
Department of Chemistry KTH Royal Institute of Technology Stockholm SE‐10044 Sweden
Malin Lill
Department of Chemistry KTH Royal Institute of Technology Stockholm SE‐10044 Sweden
Ziwei Fan
Department of Chemistry KTH Royal Institute of Technology Stockholm SE‐10044 Sweden
Kevin Breitwieser
Department of Chemistry KTH Royal Institute of Technology Stockholm SE‐10044 Sweden
Jai White
Department of Chemistry KTH Royal Institute of Technology Stockholm SE‐10044 Sweden
Sergio Pérez Morente
Department of Chemistry KTH Royal Institute of Technology Stockholm SE‐10044 Sweden
Mårten Ahlquist
Department of Chemistry KTH Royal Institute of Technology Stockholm SE‐10044 Sweden
Helena Lundberg