Efficient Assembly of Functional RNA by <i>in Situ</i> Phosphate Activation and Loop-Closing Ligation

J Jian Zhang A Aleksandar Radakovic F Filip Bošković (Howard Hughes Medical Institute, Department of Chemistry) H Harry R. M. Aitken (Howard Hughes Medical Institute) L Long-Fei Wu (Frontiers Science Center for Transformative Molecules, State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, Zhangjiang Institute for Advanced Study) J Jack W. Szostak (Department of Chemistry)

Article Details

Volume / Issue Vol. 147, Issue 43
Published October 29, 2025
Pages 39212-39222
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (6)

J

Jian Zhang

A

Aleksandar Radakovic

F

Filip Bošković

Howard Hughes Medical Institute, Department of Chemistry

H

Harry R. M. Aitken

Howard Hughes Medical Institute

L

Long-Fei Wu

Frontiers Science Center for Transformative Molecules, State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, Zhangjiang Institute for Advanced Study

J

Jack W. Szostak

Department of Chemistry