Effective SMOTE boost with deep learning for IDC identification in whole-slide images

M Mudhafar Jalil Jassim Ghrabat A Arkan A. Ghaib A Auhood Al-Hossenat Z Zaid Ameen Abduljabbar V Vincent Omollo Nyangaresi J Junchao Ma A Abdulla J. Y. Aldarwish I Iman Qays Abduljaleel D Dhafer G. Honi H Husam A. Neamah

Abstract

Breast cancer is highlighted in recent research as one of the most prevalent types of cancer. Timely identification is essential for enhancing patient results and decreasing fatality rates. Utilizing computer-assisted detection and diagnosis early on may greatly improve the chances of recovery by accurately predicting outcomes and developing suitable treatment plans. Grading breast cancer properly, especially evaluating nuclear atypia, is difficult owing to faults and inconsistencies in slide preparation and the intricate nature of tissue patterns. This work explores the capability of deep learning to extract characteristics from histopathology photos of breast cancer. The research introduces a new method called SMOTE-based Convolutional Neural Network (CNN) technology to detect areas impacted by Invasive Ductal Carcinoma (IDC) in whole slide pictures. The trials used a dataset of 162 individuals with IDC, split into training (113 photos) and testing (49 images) groups. Every model was subjected to individual testing. The SMO_CNN model we developed demonstrated exceptional testing and training accuracies of 98.95% and 99.20% respectively, surpassing CNN, VGG19, and ResNet50 models. The results highlight the effectiveness of the created model in properly detecting IDC-affected tissue areas, showing great promise for improving breast cancer diagnosis and treatment planning. We surpassing other models as such, CNN, VGG19, ResNet50.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 20, Issue 9
Published September 03, 2025
Pages e0329078
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (10)

M

Mudhafar Jalil Jassim Ghrabat

A

Arkan A. Ghaib

A

Auhood Al-Hossenat

Z

Zaid Ameen Abduljabbar

V

Vincent Omollo Nyangaresi

J

Junchao Ma

A

Abdulla J. Y. Aldarwish

I

Iman Qays Abduljaleel

D

Dhafer G. Honi

H

Husam A. Neamah