Dual Proton/Anion Binding Through Reciprocal Allostery in Platinum(II) Lantern‐Shaped Cages

Z Zack T. Avery (Research School of Chemistry Australian National University Canberra ACT 2601 Australia) E Elizabeth C. Elphick (Research School of Chemistry Australian National University Canberra ACT 2601 Australia) M Michael G. Gardiner (Research School of Chemistry, Australian National University) R Rosemary J. Goodwin (Research School of Chemistry Australian National University Canberra ACT 2601 Australia) J Junming Ho (School of Chemistry University of New South Wales Sydney NSW 2052 Australia) M Martin D. Peeks (School of Chemistry University of New South Wales Sydney New South Wales Australia) D Dan Preston (Research School of Chemistry Australian National University Canberra ACT 2601 Australia)

Abstract

Abstract Reciprocal allosteric regulation, where binding events influence each other simultaneously, is a key target for supramolecular chemists designing biomimetic systems. Platinum(II) lantern‐shaped cages, formed from a series of ligands bearing central protonatable sites of varied basicity through rational tuning of the backbone, featured nuanced dual action host‐guest chemistry. This reveals the first example of reciprocal allostery in a supramolecular system, between protonation and anion binding. Switching studies were conducted using acid/base and silver/chloride stimuli, with single and multi‐anion systems.

Article Details

Volume / Issue Vol. 65, Issue 2
Published January 09, 2026
ISSN 1433-7851
Publisher Wiley

Journal Info

Angewandte Chemie International Edition

Wiley

ISSN: 1433-7851 Physical Sciences

Authors (7)

Z

Zack T. Avery

Research School of Chemistry Australian National University Canberra ACT 2601 Australia

E

Elizabeth C. Elphick

Research School of Chemistry Australian National University Canberra ACT 2601 Australia

M

Michael G. Gardiner

Research School of Chemistry, Australian National University

R

Rosemary J. Goodwin

Research School of Chemistry Australian National University Canberra ACT 2601 Australia

J

Junming Ho

School of Chemistry University of New South Wales Sydney NSW 2052 Australia

M

Martin D. Peeks

School of Chemistry University of New South Wales Sydney New South Wales Australia

D

Dan Preston

Research School of Chemistry Australian National University Canberra ACT 2601 Australia