Dual bispecific protein engagers targeting mesothelin and NECTIN2 deliver CD3/CD28 signals to activate cytotoxic T cells against colorectal cancer patient-derived organoids

S Suyanee Thongchot K Kamonlapat Supimon N Nattaporn Phanthaphol P Pattara Kanoksing T Titaporn Mitchasin T Thaweesak Chieochansin W Woramin Riansuwan S Siriluck Prapasrivorakul P Pornraksa Ovartchaiyapong A Aitsariya Mongkhonsupphawan S Surat Phumphuang M Mutita Junking P Pa-thai Yenchitsomanus P Peti Thuwajit C Chanitra Thuwajit

Article Details

Volume / Issue Vol. 1, Issue 1
Published July 29, 2026
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (15)

S

Suyanee Thongchot

K

Kamonlapat Supimon

N

Nattaporn Phanthaphol

P

Pattara Kanoksing

T

Titaporn Mitchasin

T

Thaweesak Chieochansin

W

Woramin Riansuwan

S

Siriluck Prapasrivorakul

P

Pornraksa Ovartchaiyapong

A

Aitsariya Mongkhonsupphawan

S

Surat Phumphuang

M

Mutita Junking

P

Pa-thai Yenchitsomanus

P

Peti Thuwajit

C

Chanitra Thuwajit