Dopamine-Induced Tau Modification Prevents Pathological Phosphorylation and Generates a Distinct Fibril Polymorph

Z Zhengtao Liu (Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry) X Xiang Li Q Qianwen Wang (Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering) K Kaien Liu (Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry) W Wen Zeng D Danni Li (Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry) K Kun Zhao Y Yeyang Ma (Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry) H Houfang Long (Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry) S Shengnan Zhang (Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry) D Dan Li B Bo Sun W Weidong Le (Key Laboratory of Liaoning Province for Research on the Pathogenic Mechanisms of Neurological Diseases) C Chu Wang Z Zhuohao He (Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry) W Wenyan Kang (Department of Neurology and Institute of Neurology, Ruijin Hospital) W Weidi Xiao (Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies) C Cong Liu

Article Details

Volume / Issue Vol. 148, Issue 4
Published February 04, 2026
Pages 4729-4742
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (18)

Z

Zhengtao Liu

Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry

X

Xiang Li

Q

Qianwen Wang

Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering

K

Kaien Liu

Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry

W

Wen Zeng

D

Danni Li

Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry

K

Kun Zhao

Y

Yeyang Ma

Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry

H

Houfang Long

Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry

S

Shengnan Zhang

Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry

D

Dan Li

B

Bo Sun

W

Weidong Le

Key Laboratory of Liaoning Province for Research on the Pathogenic Mechanisms of Neurological Diseases

C

Chu Wang

Z

Zhuohao He

Interdisciplinary Research Center on Biology and Chemistry, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry

W

Wenyan Kang

Department of Neurology and Institute of Neurology, Ruijin Hospital

W

Weidi Xiao

Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies

C

Cong Liu