DNA Tetrahedron-Driven Multivalent Proteolysis-Targeting Chimeras: Enhancing Protein Degradation Efficiency and Tumor Targeting

S Shiqing Li (New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Key Laboratory of Analysis and Testing Technology for Food Safety and Health, College of Chemistry) T Tao Zeng Z Zhixing Wu (New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou 350108, People’s Republic of China) J Jiabao Huang (State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, People’s Republic of China) X Xiuping Cao (New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Key Laboratory of Analysis and Testing Technology for Food Safety and Health, College of Chemistry) Y Yana Liu (New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Key Laboratory of Analysis and Testing Technology for Food Safety and Health, College of Chemistry) S Shiyan Bai (New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Key Laboratory of Analysis and Testing Technology for Food Safety and Health, College of Chemistry) Q Qi Chen C Chunsen Li (State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter) C Chunhua Lu (New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Key Laboratory of Analysis and Testing Technology for Food Safety and Health, College of Chemistry) H Huanghao Yang (New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry)

Article Details

Volume / Issue Vol. 147, Issue 2
Published January 15, 2025
Pages 2168-2181
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (11)

S

Shiqing Li

New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Key Laboratory of Analysis and Testing Technology for Food Safety and Health, College of Chemistry

T

Tao Zeng

Z

Zhixing Wu

New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou 350108, People’s Republic of China

J

Jiabao Huang

State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, People’s Republic of China

X

Xiuping Cao

New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Key Laboratory of Analysis and Testing Technology for Food Safety and Health, College of Chemistry

Y

Yana Liu

New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Key Laboratory of Analysis and Testing Technology for Food Safety and Health, College of Chemistry

S

Shiyan Bai

New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Key Laboratory of Analysis and Testing Technology for Food Safety and Health, College of Chemistry

Q

Qi Chen

C

Chunsen Li

State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter

C

Chunhua Lu

New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Key Laboratory of Analysis and Testing Technology for Food Safety and Health, College of Chemistry

H

Huanghao Yang

New Cornerstone Science Laboratory, MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry