Journal of the American Chemical Society

Distal Mutations in a Designed Retro-Aldolase Alter Loop Dynamics to Shift and Accelerate the Rate-Limiting Step

S Serena E. Hunt (Department of Chemistry and Biomolecular Sciences) C Cindy Klaus (Department of Chemistry and Biomolecular Sciences) A Aqza E. John (Institut de Química Computacional i Catàlisi and Departament de Química, Universitat de Girona, C/M. Aurèlia Capmany, 69, 17003 Girona, Spain) N Niayesh Zarifi (Department of Chemistry and Biomolecular Sciences) A Alec Martinez (Department of Chemistry and Biochemistry) F Ferran Feixas (Institut de Química Computacional i Catàlisi (IQCC) and Departament de Química, Universitat de Girona, Campus Montilivi, 17003 Girona, Catalonia, Spain) M Marc Garcia-Borràs (Institut de Química Computacional i Catàlisi and Departament de Química, Universitat de Girona, C/M. Aurèlia Capmany, 69, 17003 Girona, Spain) M Michael C. Thompson (Department of Chemistry and Biochemistry) R Roberto A. Chica (Department of Chemistry and Biomolecular Sciences)
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Article Details

Volume / Issue Vol. 147, Issue 34
Published August 27, 2025
Pages 30723-30736
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society
ISSN: 0002-7863 Physical Sciences

Authors (9)

S

Serena E. Hunt

Department of Chemistry and Biomolecular Sciences

C

Cindy Klaus

Department of Chemistry and Biomolecular Sciences

A

Aqza E. John

Institut de Química Computacional i Catàlisi and Departament de Química, Universitat de Girona, C/M. Aurèlia Capmany, 69, 17003 Girona, Spain

N

Niayesh Zarifi

Department of Chemistry and Biomolecular Sciences

A

Alec Martinez

Department of Chemistry and Biochemistry

F

Ferran Feixas

Institut de Química Computacional i Catàlisi (IQCC) and Departament de Química, Universitat de Girona, Campus Montilivi, 17003 Girona, Catalonia, Spain

M

Marc Garcia-Borràs

Institut de Química Computacional i Catàlisi and Departament de Química, Universitat de Girona, C/M. Aurèlia Capmany, 69, 17003 Girona, Spain

M

Michael C. Thompson

Department of Chemistry and Biochemistry

R

Roberto A. Chica

Department of Chemistry and Biomolecular Sciences

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