Discovery of RNA-Reactive Small Molecules Guides the Design of Electrophilic Modules for RNA-Specific Covalent Binders

N Noah A. Springer (Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States) P Patrick R. A. Zanon (The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Department of Chemistry, 130 Scripps Way, Jupiter, Florida 33458, United States) A Amirhossein Taghavi (Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology (UF-Scripps), 130 Scripps Way, Jupiter, Florida 33458, United States) K Kisu Sung (Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States) M Matthew D. Disney (Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States)

Article Details

Volume / Issue Vol. 147, Issue 38
Published September 24, 2025
Pages 34271-34282
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (5)

N

Noah A. Springer

Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States

P

Patrick R. A. Zanon

The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Department of Chemistry, 130 Scripps Way, Jupiter, Florida 33458, United States

A

Amirhossein Taghavi

Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology (UF-Scripps), 130 Scripps Way, Jupiter, Florida 33458, United States

K

Kisu Sung

Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States

M

Matthew D. Disney

Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States