Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes

W Woong Sub Byun (Department of Chemical and Systems Biology, ChEM-H, and Stanford Cancer Institute, Stanford School of Medicine) Z Zhe Zhuang (Department of Chemical and Systems Biology, ChEM-H and Stanford Cancer Institute, Stanford Medical School) A Anna P. Hnatiuk (Stanford Cardiovascular Institute, Department of Medicine, and Department of Chemical and Systems Biology) C Cyrus Jin (Department of Cancer Biology) Z Zixuan Jiang (Department of Chemical and Systems Biology, ChEM-H, and Stanford Cancer Institute, Stanford School of Medicine) K Kheewoong Baek (Department of Cancer Biology, Dana–Farber Cancer Institute, Boston, MA 02215, USA.) E Evelyn Chao (Department of Chemical and Systems Biology, ChEM-H, and Stanford Cancer Institute, Stanford School of Medicine) K Katherine A. Donovan E Eric S. Fischer M Mark Mercola (Stanford Cardiovascular Institute, Department of Medicine, and Department of Chemical and Systems Biology) N Nathanael S. Gray

Article Details

Volume / Issue Vol. 147, Issue 39
Published October 01, 2025
Pages 35481-35492
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (11)

W

Woong Sub Byun

Department of Chemical and Systems Biology, ChEM-H, and Stanford Cancer Institute, Stanford School of Medicine

Z

Zhe Zhuang

Department of Chemical and Systems Biology, ChEM-H and Stanford Cancer Institute, Stanford Medical School

A

Anna P. Hnatiuk

Stanford Cardiovascular Institute, Department of Medicine, and Department of Chemical and Systems Biology

C

Cyrus Jin

Department of Cancer Biology

Z

Zixuan Jiang

Department of Chemical and Systems Biology, ChEM-H, and Stanford Cancer Institute, Stanford School of Medicine

K

Kheewoong Baek

Department of Cancer Biology, Dana–Farber Cancer Institute, Boston, MA 02215, USA.

E

Evelyn Chao

Department of Chemical and Systems Biology, ChEM-H, and Stanford Cancer Institute, Stanford School of Medicine

K

Katherine A. Donovan

E

Eric S. Fischer

M

Mark Mercola

Stanford Cardiovascular Institute, Department of Medicine, and Department of Chemical and Systems Biology

N

Nathanael S. Gray