Discovery of a small molecule TLR3 agonist adjuvant

B Branden Lee D Danica Dong E Etsuro Nanishi J John Mark Awad K Kimia Z. Abedi Y Yoshine Saito F Francesco Borriello S Soumik Barman B Byron Brook A Aisling Kelly M Manisha Menon C Constance Marques-Mourlet M Maansi V. Gupta I Ida Lister C Chiwoo Oh K Kevin Lyskawa M Morgan Goetz K Kristina Walker W Wing Ki Cheng S Spencer E. Brightman P Pankaj Sharma T Timothy R. O’Meara K Katherine Chew D Daniel Vieira K Kevin Ryff C Cali Sweitzer S Sanya Thomas S Simon D. van Haren M Matthew Pettengill H Hyuk-Soo Seo (Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School) S Sirano Dhe-Paganon (Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School) W Wei Zhang O Ofer Levy (Harvard Medical School) D David J. Dowling