Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in bacteria

B Belen Sotomayor T Thomas C. Donahue S Sai Pooja Mahajan M May N. Taw S Sophia W. Hulbert E Erik J. Bidstrup D D. Natasha Owitipana A Alexandra Pang X Xu Yang S Souvik Ghosal (Department of Chemistry and Chemical Biology, Cornell University) C Christopher A. Alabi (Robert F. Smith School of Chemical and Biomolecular Engineering, Cornell University) P Parastoo Azadi J Jeffrey J. Gray (Program in Molecular Biophysics, Johns Hopkins University) M Michael C. Jewett (Department of Bioengineering, Stanford University) L Lai-Xi Wang M Matthew P. DeLisa (Robert F. Smith School of Chemical and Biomolecular Engineering, Cornell University)

Article Details

Volume / Issue Vol. 16, Issue 1
Published July 04, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (16)

B

Belen Sotomayor

T

Thomas C. Donahue

S

Sai Pooja Mahajan

M

May N. Taw

S

Sophia W. Hulbert

E

Erik J. Bidstrup

D

D. Natasha Owitipana

A

Alexandra Pang

X

Xu Yang

S

Souvik Ghosal

Department of Chemistry and Chemical Biology, Cornell University

C

Christopher A. Alabi

Robert F. Smith School of Chemical and Biomolecular Engineering, Cornell University

P

Parastoo Azadi

J

Jeffrey J. Gray

Program in Molecular Biophysics, Johns Hopkins University

M

Michael C. Jewett

Department of Bioengineering, Stanford University

L

Lai-Xi Wang

M

Matthew P. DeLisa

Robert F. Smith School of Chemical and Biomolecular Engineering, Cornell University